عنوان مقاله:

نویسندگان:

تینا ربیعی، پارسا موسوی، حمید یگانه، سعید نوری خراسانی، ایرج محمدپور بلترک

Compared with traditional wound closure methods tissue adhesives are less likely to damage the tissues and can promote wound healing without scare marks. This work aims to synthesize and evaluate a novel tannin-based UV-curable tissue adhesive. Tannic acid a natural polyphenol with potential antibacterial activity was selected as an adhesion promoter and combined with an unsaturated non-isocyanate urethane prepolymer prepared from soybean oil itaconic acid and CO2 gas. Proper formulations of these materials and multifunctional thiols were utilized as a high-performance tissue adhesive. This bio-based tissue adhesive represents desirable properties such as good adhesion strength proper biocompatibility towards fibroblast cells fast and effective curing process toward UV irradiation and acceptable swelling ratio.

Tannic acid itaconic acid tissue adhesive soybean oil Non-isocyanate PU

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ربیعی، تینا، موسوی، پارسا، یگانه، حمید، نوری خراسانی، سعید، محمدپور بلترک، ایرج، 1402، سنتز و ارزیابی چسب بافتی مشتق از تانن، كنگره بين المللي فرآورده‌هاي طبيعي شفابخش، https://conf.ui.ac.ir/fa/archive_index.php?c=remedcong&aid=1506667