چکیده

Statement of Problem Leukemia is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. The cause of leukemia is unknown but some factors put people at higher risk. Treatment methods include radiation therapy chemotherapy treatment immunotherapy stem cell therapy etc. In the studies have been done on several extracts of different plants it was found that the aerial parts of Artemisia.vulgaris have been able to suppress the growth of leukemia cells. Research Purpose The purpose of this study is to review the studies conducted on the effective herbal medicine (Artemisia.vulgaris) in the treatment of leukemia. Research Method The review method is to search in Pubmed and Google Scholar Results and Conclusion the aerial parts of Artemisia.vulgaris are being used as an anthelminthic an antiseptic an antispasmodic and a tonic for vital organs and for disorders including hepatitis. They are able to suppress the growth of leukemia cells. Screening shows that 1 8 Cineol (Eucalyptol) extracted from A.vulgarisis kills leukemia cells in vitro. In the other study the results demonstrated that the essential oil-induced apoptosis in HL-60 leukemic cell line was mediated by caspase-dependent pathways involving caspase-3 -9 and -8 which were initiated by Bcl-2 Bax Bid-dependent. The results recommended that A.vulgaris might be a promising source of new anticancer agents.

کليدواژه ها

Herbal medicines Leukemia HL-60 Artemisia.vulgaris

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فرزانه اوحدی , 1402 , Effective herbal medicine (Artemisia.vulgaris) in the treatment of Leukemia disease , كنگره بين المللي فرآورده‌هاي طبيعي شفابخش